Surgical Pathophysiology

Aasen A.O. acid Acta Chir Scand acute pancreatitis adult respiratory distress Ann Surg Appl Physiol aprotinin ARDS arterial bacterial blood cancer capillary cardiac circulation Clin Invest clinical coagulation complement activation concentrations deep vein thrombosis demonstrated disease dose edema effect endothelial cells endotoxemia endotoxin enzyme experimental extravascular fibrin fibrinolytic fibrinolytic activity fluid function gastric gastrin gastrointestinal glucose granulocytes hemodilution hemorrhagic hormones human hypoxanthine hypoxia Immunol increased induced infection infusion inhibition inhibitor interleukin intestinal ischemia leukocytes levels lung injury lung water macrophages mechanisms mediators metabolic microvascular mucosal multiple organ failure necrosis factor neutrophils normal oxygen radicals patients peptide perfused peritoneal permeability plasma kallikrein plasmin plasminogen activator platelet postoperative pressure prophylaxis prostaglandin protease protein pulmonary radiation enteropathy release respiratory distress syndrome response role sepsis septic shock septicemia stimulation studies substrate superoxide Surg Res surgery surgical t-PA Thromb Res tissue trauma treatment trypsin tumor necrosis ulcer vascular xanthine oxidase