Page images
PDF
EPUB
[graphic][subsumed][ocr errors][subsumed][ocr errors][subsumed][subsumed][ocr errors][ocr errors][subsumed][ocr errors][ocr errors][subsumed][subsumed][subsumed][ocr errors][subsumed][ocr errors][subsumed][subsumed][subsumed][subsumed][subsumed][ocr errors][ocr errors][subsumed][subsumed][subsumed][ocr errors][subsumed][ocr errors][ocr errors][ocr errors][subsumed][subsumed][subsumed][subsumed][subsumed][subsumed]
[blocks in formation]

CARDISS COLLINS, Illinois
GLENN ENGLISH, Oklahoma
HENRY A. WAXMAN, California
TED WEISS, New York

KE SYNAR, Oklahoma

PHEN L. NEAL, North Carolina
UG BARNARD, JR., Georgia
M LANTOS, California

BERT E. WISE, JR., West Virginia
BARA BOXER, California
JOR R. OWENS, New York
LPHUS TOWNS, New York
ERDREICH, Alabama
ALD D. KLECZKA, Wisconsin
ERT G. BUSTAMANTE, Texas
THEW G. MARTINEZ, California
ALD M. PAYNE, New Jersey
GARY A. CONDIT, California
PATSY T. MINK, Hawaii
RAY THORNTON, Arkansas

COLLIN C. PETERSON, Minnesota

ROSA L. DELAURO, Connecticut
CHARLES J. LUKEN, Ohio

JOHN W. COX, JR., Illinois

FRANK HORTON, New York
WILLIAM F. CLINGER, JR., Pennsylvania
AL MCCANDLESS, California
J. DENNIS HASTERT, Illinois
JON L. KYL, Arizona

CHRISTOPHER SHAYS, Connecticut
STEVEN SCHIFF, New Mexico

C. CHRISTOPHER COX, California
CRAIG THOMAS, Wyoming

ILEANA ROS-LEHTINEN, Florida
RONALD K. MACHTLEY, Rhode Island
DICK ZIMMER, New Jersey

WILLIAM H. ZELIFF, JR., New Hampshire
DAVID L. HOBSON, Ohio

SCOTT L. KLUG, Wisconsin

BERNARD SANDERS, Vermont (Independent)

[blocks in formation]

CONTENTS

[ocr errors][merged small][subsumed][merged small]

Lundberg, George, M.D., editor, Journal of the American Medical Asso-
ciation:

Articles dated May 8, 1991, and June 12, 1991, relating to promotion-
al cruise offered by Collagen Corp...

139

[merged small][ocr errors]

Letters, statements, etc., submitted for the record by—Continued

Weiss, Hon. Ted, a Representative in Congress from the State of New York, and chairman, Human Resources and Intergovernmental Relations Subcommittee-Continued

Page

Article dated July 27, 1989, from the New England Journal of Medi-
cine entitled "Embryonic Retinoid Concentrations After Material
Intake of Isotretinoin".

190

Article describing underreporting of adverse reactions, coauthored by
an FDA scientist..

223

Documents describing collagen injections to the lips
Documents regarding FDA concerns in 1987

237

177

197

.......

FDA document describing problems with Dow Corning study
FDA Memorandum dated September 10, 1990, and letter dated Sep-
tember 21, 1990, describing research problems......
Litigation of Celia Anderson, regarding liquid silicone injections.....
Material selected from press conference..
Memorandum dated February 9, 1983, regarding meeting with Dr. Al
Kligman, regarding aging skin, and article from Journal of Ameri-
can Association dated November 14, 1990, entitled "The Federal
Regulation of Prescription Drug Advertising and Promotion".
Memorandum dated July 26, 1984, regarding Orentreich investiga-
tion......

Pamphlet from Collagen Corp. entitled "Injectable Collagen. The end
of the lines"

Press release describing the NIH consensus conference conclusions.....
Report dated August 24, 1990, regarding limited applications for
silicone injections, submitted by Dow Corning Corp..........
APPENDIXES

Appendix 1.-Collagen Corp.'s response to invitation to testify
Appendix 2.-Additional information provided by FDA...

Appendix 3.-Honoraria and other payments to researchers re Retin-A.
Appendix 4.-CDC review of collagen and PM/DM...

Appendix 5.—Additional documents regarding Collagen Corp........

203

217

160

167

192

230

183

213

259

263

340

367

373

« PreviousContinue »