Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page xvii
... standard textbooks, this book takes an empirical, practical approach. It does not simply use examples from the ... standards of quality we have always tried to maintain for the Journal, and that it will find favor with a broad cross ...
... standard textbooks, this book takes an empirical, practical approach. It does not simply use examples from the ... standards of quality we have always tried to maintain for the Journal, and that it will find favor with a broad cross ...
Page xxiv
... standard methods of investigating treatment and prevention (discussed in Chapters 4, 5, and 6) are presented together with some discussion of their difficulties and of precautions that can be taken to improve their strength. The five ...
... standard methods of investigating treatment and prevention (discussed in Chapters 4, 5, and 6) are presented together with some discussion of their difficulties and of precautions that can be taken to improve their strength. The five ...
Page 8
... standard well-known instrument for the purpose; examples include the New York Heart Association Index of Cardiac Function, the Karnofsky Scale for disability in cancer patients, and the Mini Mental State Examination for cognitive ...
... standard well-known instrument for the purpose; examples include the New York Heart Association Index of Cardiac Function, the Karnofsky Scale for disability in cancer patients, and the Mini Mental State Examination for cognitive ...
Page 9
... standard specimens. Samples of study records may be checked against clinical records. Visits and audits by personnel from a center that is charged with responsibility for quality control may be routinely conducted in multicenter studies ...
... standard specimens. Samples of study records may be checked against clinical records. Visits and audits by personnel from a center that is charged with responsibility for quality control may be routinely conducted in multicenter studies ...
Page 10
... standard therapy. An infinite supply of data gathered in this way could at best resolve whether it was better to receive the new therapy within two hours or the standard therapy after two hours. Not even an infinitely large study could ...
... standard therapy. An infinite supply of data gathered in this way could at best resolve whether it was better to receive the new therapy within two hours or the standard therapy after two hours. Not even an infinitely large study could ...
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes