Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page xxvi
... shows that many published papers with low power may have missed sizable medical improvements. Chapter 20 (Writing about Numbers) describes some common but easily avoided perils to those whose experience is primarily in working with ...
... shows that many published papers with low power may have missed sizable medical improvements. Chapter 20 (Writing about Numbers) describes some common but easily avoided perils to those whose experience is primarily in working with ...
Page 5
... show; and induction, the process of reaching conclusions about future cases on the basis of the data in the present study. The design of an investigation needs to take these concepts into account. The publication reporting the study ...
... show; and induction, the process of reaching conclusions about future cases on the basis of the data in the present study. The design of an investigation needs to take these concepts into account. The publication reporting the study ...
Page 11
... show strong and roughly equal positive associations between height and weight and between girth and weight. We must draw on other information to support the proposition that by increasing the weight of a man we will increase his girth ...
... show strong and roughly equal positive associations between height and weight and between girth and weight. We must draw on other information to support the proposition that by increasing the weight of a man we will increase his girth ...
Page 14
... show the probabilities of more complex kinds of outcomes. Thus, if two diagnostic tests, A and B, are used and the outcomes measured are survival to one year or death in the same period, then the infinite-data case would answer all ...
... show the probabilities of more complex kinds of outcomes. Thus, if two diagnostic tests, A and B, are used and the outcomes measured are survival to one year or death in the same period, then the infinite-data case would answer all ...
Page 22
... shows that the study has little chance of providing a useful answer under the existing constraints of time or budget. Thus, if eligible subjects must have a disease D, with low prevalence, it may not be realistic to undertake the study ...
... shows that the study has little chance of providing a useful answer under the existing constraints of time or budget. Thus, if eligible subjects must have a disease D, with low prevalence, it may not be realistic to undertake the study ...
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes