Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page xxv
... reported so much discussion about P values since the first edition that Chapter 10 has been completely rewritten. Section III then turns to five specific sets of techniques. Two of these deal with major problems in statistics — simple ...
... reported so much discussion about P values since the first edition that Chapter 10 has been completely rewritten. Section III then turns to five specific sets of techniques. Two of these deal with major problems in statistics — simple ...
Page xxvi
... reported in a set of 67 papers on randomized clinical trials published in four leading general medical journals. Of 11 simple, important aspects of statistical design and analysis in each of these papers, only about 56 percent were ...
... reported in a set of 67 papers on randomized clinical trials published in four leading general medical journals. Of 11 simple, important aspects of statistical design and analysis in each of these papers, only about 56 percent were ...
Page 5
... reported results often requires an understanding of statistical issues and of the way in which the investigators have addressed those issues. Even more striking than the range of clinical studies where 5 Chapter 1: Statistical Concepts ...
... reported results often requires an understanding of statistical issues and of the way in which the investigators have addressed those issues. Even more striking than the range of clinical studies where 5 Chapter 1: Statistical Concepts ...
Page 23
... reported. It is desirable to publish the raw data, though often there are obstacles — such as editorial policies — to doing so. At a minimum, the raw data should be carefully labeled and filed, not melded into the next analysis or ...
... reported. It is desirable to publish the raw data, though often there are obstacles — such as editorial policies — to doing so. At a minimum, the raw data should be carefully labeled and filed, not melded into the next analysis or ...
Page 25
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes