Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page xxiii
... reasons are unrecognized influences on the data, errors in critical assumptions about relative magnitudes, and uncertainty about generalizing results in complicated situations, such as moving from data acquired from animal experiments ...
... reasons are unrecognized influences on the data, errors in critical assumptions about relative magnitudes, and uncertainty about generalizing results in complicated situations, such as moving from data acquired from animal experiments ...
Page 12
... reason related to mortality in the patients in this study. Had there not been a placebo group, the confounding between the quantity of the drug actually taken and unknown factors related to survival might have gone unnoticed, and the ...
... reason related to mortality in the patients in this study. Had there not been a placebo group, the confounding between the quantity of the drug actually taken and unknown factors related to survival might have gone unnoticed, and the ...
Page 29
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Page 33
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes