Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page 11
... population having that value of x (receiving that dose). Now, though individual variability still attends the pair of variables x and y, there is a well-defined single curve relating the average of one variable to stated values of the ...
... population having that value of x (receiving that dose). Now, though individual variability still attends the pair of variables x and y, there is a well-defined single curve relating the average of one variable to stated values of the ...
Page 13
... population to capture the ideas discussed here under the rubric of the infinite-data case. A sometimes troublesome point is illustrated by the following example, which deals with motorcycle accident fatalities and helmet laws.4 In ...
... population to capture the ideas discussed here under the rubric of the infinite-data case. A sometimes troublesome point is illustrated by the following example, which deals with motorcycle accident fatalities and helmet laws.4 In ...
Page 15
... population tend to be smaller when nis greater. Moreover, many important sample statistics from random samples are also increasingly similar with larger sample sizes. Therefore, the random variation of statistics can be reduced by using ...
... population tend to be smaller when nis greater. Moreover, many important sample statistics from random samples are also increasingly similar with larger sample sizes. Therefore, the random variation of statistics can be reduced by using ...
Page 16
... population so that every possible sample of size n has the same probability of being chosen; this is called a simple random sample. The laws of probability are directly applicable and enable us to make definite statements about the ...
... population so that every possible sample of size n has the same probability of being chosen; this is called a simple random sample. The laws of probability are directly applicable and enable us to make definite statements about the ...
Page 17
... population mean lies between 20.6 and 21.3” or “It is a 19-to-l bet that the population mean is negative.” Other forms for stating statistical inferences exist; they also include a numerical statement about the population or infinite ...
... population mean lies between 20.6 and 21.3” or “It is a 19-to-l bet that the population mean is negative.” Other forms for stating statistical inferences exist; they also include a numerical statement about the population or infinite ...
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes