Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page xxvi
... issues that frequently arise in preparing a clinical paper containing numerical data. Details of what to publish may vary a lot from one kind of study to another. Chapter 17 (Reporting on Methods) presents an empirical study of whether ...
... issues that frequently arise in preparing a clinical paper containing numerical data. Details of what to publish may vary a lot from one kind of study to another. Chapter 17 (Reporting on Methods) presents an empirical study of whether ...
Page xxvii
... issues and approaches. New York: Marcel Dekker, 1983. 2. Ingelfinger JA, Mosteller F, Thibodeau LA, Ware JH. Biostatistics in clinical medicine. 2nd ed. New York: Macmillan, 1987. Taylor & Francis Taylor & Francis Group http ...
... issues and approaches. New York: Marcel Dekker, 1983. 2. Ingelfinger JA, Mosteller F, Thibodeau LA, Ware JH. Biostatistics in clinical medicine. 2nd ed. New York: Macmillan, 1987. Taylor & Francis Taylor & Francis Group http ...
Page 5
... issues and of the way in which the investigators have addressed those issues. Even more striking than the range of clinical studies where 5 Chapter 1: Statistical Concepts Fundamental to Investigations.
... issues and of the way in which the investigators have addressed those issues. Even more striking than the range of clinical studies where 5 Chapter 1: Statistical Concepts Fundamental to Investigations.
Page 6
... issues arise is the importance of a few statistical concepts that apply to many different types of studies. This ... issue raised by this question is sometimes labeled internal validity. A second question follows: If the data had been ...
... issues arise is the importance of a few statistical concepts that apply to many different types of studies. This ... issue raised by this question is sometimes labeled internal validity. A second question follows: If the data had been ...
Page 7
... issue sometimes labeled external validity. Internal validity is primarily a statistical issue; external validity can be evaluated only with the help of expertise and judgment in areas outside statistics. The next four sections of this ...
... issue sometimes labeled external validity. Internal validity is primarily a statistical issue; external validity can be evaluated only with the help of expertise and judgment in areas outside statistics. The next four sections of this ...
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes