Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page iv
... drug formulary and the drug companies' and device or material manufacturers' printed instructions, and their websites, before administering or utilizing any of the drugs, devices or materials mentioned in this book. This book does not ...
... drug formulary and the drug companies' and device or material manufacturers' printed instructions, and their websites, before administering or utilizing any of the drugs, devices or materials mentioned in this book. This book does not ...
Page xxvii
... drugs, devices, and procedures should be brought into the medical system. Often the reader of the literature must assemble information about a particular topic from many papers. This assembly must go beyond the methods of the usual ...
... drugs, devices, and procedures should be brought into the medical system. Often the reader of the literature must assemble information about a particular topic from many papers. This assembly must go beyond the methods of the usual ...
Page 8
... Drug A administered by mouth in a syrup also includes the syrup. (A series of deaths in the early days of sulfanilamide treatment attests tragically to this fact.1) A medicine prescribed is not necessarily a medication actually used ...
... Drug A administered by mouth in a syrup also includes the syrup. (A series of deaths in the early days of sulfanilamide treatment attests tragically to this fact.1) A medicine prescribed is not necessarily a medication actually used ...
Page 10
... drugs. If a drug is intended to treat a disease affecting mainly elderly patients, and if younger subjects are expected to be used in a clinical trial, this question should arise before the study begins: What could unlimited data about ...
... drugs. If a drug is intended to treat a disease affecting mainly elderly patients, and if younger subjects are expected to be used in a clinical trial, this question should arise before the study begins: What could unlimited data about ...
Page 11
... drug usually produce larger effects. A useful way to make this idea of a statistical relationship more amenable to quantitative treatment is the concept of regression. Think of two variables x (dose) and y (response). We define the ...
... drug usually produce larger effects. A useful way to make this idea of a statistical relationship more amenable to quantitative treatment is the concept of regression. Think of two variables x (dose) and y (response). We define the ...
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes