Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page viii
... Crossover and Self-Controlled Designs in Clinical Research Thomas A. Louisy Philip W. Lavoriy John C. Bailarlll, and Marcia Polansky 83 Chapter 6 Studies without Internal Controls John C. BailarIIIy Thomas A. Louisy Philip W. Lavori ...
... Crossover and Self-Controlled Designs in Clinical Research Thomas A. Louisy Philip W. Lavoriy John C. Bailarlll, and Marcia Polansky 83 Chapter 6 Studies without Internal Controls John C. BailarIIIy Thomas A. Louisy Philip W. Lavori ...
Page 21
... to compare the treatments; comparison of treatments in identical twins epitomizes this approach. The crossover design goes further, using both treatments in every subject, Section I Broad Concepts and Analytic Techniques 21.
... to compare the treatments; comparison of treatments in identical twins epitomizes this approach. The crossover design goes further, using both treatments in every subject, Section I Broad Concepts and Analytic Techniques 21.
Page 22
John C. Bailar III, Frederick Mosteller. crossover design goes further, using both treatments in every subject, but results may be invalid if certain conditions do not apply to the physiologic processes under study.7 Statistical design ...
John C. Bailar III, Frederick Mosteller. crossover design goes further, using both treatments in every subject, but results may be invalid if certain conditions do not apply to the physiologic processes under study.7 Statistical design ...
Page 63
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes