Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
From inside the book
Results 1-5 of 88
Page viii
... Comparisons of Treatment Philip W. Lavoriy Thomas A. Louis, John C. BailarIIIy and Marcia Polansky 61 Chapter 5 Crossover and Self-Controlled Designs in Clinical Research Thomas A. Louisy Philip W. Lavoriy John C. Bailarlll, and Marcia ...
... Comparisons of Treatment Philip W. Lavoriy Thomas A. Louis, John C. BailarIIIy and Marcia Polansky 61 Chapter 5 Crossover and Self-Controlled Designs in Clinical Research Thomas A. Louisy Philip W. Lavoriy John C. Bailarlll, and Marcia ...
Page xxv
... comparisons of several group means (Chapter 12). They make clear that investigators must have in mind specific questions about a set of data before they can make a rational choice of analytic methods. Both chapters discuss the problems ...
... comparisons of several group means (Chapter 12). They make clear that investigators must have in mind specific questions about a set of data before they can make a rational choice of analytic methods. Both chapters discuss the problems ...
Page 8
... comparison of treatments can be difficult if at any of these phases knowledge of the treatment assigned to the patient influences other aspects of the process. Thus, if the decision to enroll each patient in the trial is made with the ...
... comparison of treatments can be difficult if at any of these phases knowledge of the treatment assigned to the patient influences other aspects of the process. Thus, if the decision to enroll each patient in the trial is made with the ...
Page 12
... comparison. The polio-vaccine trials (involving 2 million children) provide a surprising illustration. In that study the incidence of polio was clearly lower among unvaccinated children whose parents refused permission for injection ...
... comparison. The polio-vaccine trials (involving 2 million children) provide a surprising illustration. In that study the incidence of polio was clearly lower among unvaccinated children whose parents refused permission for injection ...
Page 16
... comparisons of treatments will be biased. Alertness on the part of the investigators and symmetry between treatment groups in all operational respects are the primary weapons for combating bias (hence the value of randomization and ...
... comparisons of treatments will be biased. Alertness on the part of the investigators and symmetry between treatment groups in all operational respects are the primary weapons for combating bias (hence the value of randomization and ...
Other editions - View all
Common terms and phrases
analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes