Medical Uses of StatisticsJohn C. Bailar III, Frederick Mosteller CRC Press, 2019 M05 20 - 480 pages This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results. |
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Page 11
... average, but not case by case. Thus, tall people tend to be heavier than short people; older children tend to be taller than younger ones. Higher doses of drug usually produce larger effects. A useful way to make this idea of a ...
... average, but not case by case. Thus, tall people tend to be heavier than short people; older children tend to be taller than younger ones. Higher doses of drug usually produce larger effects. A useful way to make this idea of a ...
Page 13
... average level of risk per registered motorcycle in its period, but we must doubt that any of them exactly reflects that average risk. There is clearly a role for the concept of an infinite-data case in thinking about this problem. By ...
... average level of risk per registered motorcycle in its period, but we must doubt that any of them exactly reflects that average risk. There is clearly a role for the concept of an infinite-data case in thinking about this problem. By ...
Page 14
... average, learned in grade school) is a statistic that tells about the “general size” of the sample's observations. Different samples drawn from the same infinite-data case will have somewhat differ ent sample means, so any one sample ...
... average, learned in grade school) is a statistic that tells about the “general size” of the sample's observations. Different samples drawn from the same infinite-data case will have somewhat differ ent sample means, so any one sample ...
Page 15
... average closely represents every individual value, whereas a large standard deviation tells us that this is not so. As a general rule, when random samples have small standard deviations, then sample means are more likely to be dose to ...
... average closely represents every individual value, whereas a large standard deviation tells us that this is not so. As a general rule, when random samples have small standard deviations, then sample means are more likely to be dose to ...
Page 71
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analysis applied assessment assigned authors average calculated called cancer Chapter clinical trials combined comparison considered crossover decision depends described determine discussed disease drug effects Engl England Journal error estimate example expected experiment Figure findings fitted four give given groups Health hospital hypothesis important improvement included increase indicated interpretation interval issues Journal less means measurements ment meta-analysis mortality multiple myocardial infarction N Engl observed original outcome patients percent period population possible present probability problems procedures published questions randomized readers reasons reduce REFERENCES regression relation reported requires response risk sample scientific selection shows significant sometimes specific standard statistical methods subjects Table techniques therapy tion treated treatment usually variables variance Yes Yes