Pathology of the Aging Human Nervous SystemSerge Duckett, J. C. de la Torre Oxford University Press, 2001 M05 17 - 648 pages This book is a concise and practical compendium of neuropathological information for all professionals whose responsibility it is to make diagnoses, care, and help elderly humans afflicted with neurological and/or psychiatric disorders. The term neuropathology includes a multitude of disciplines including pathology, histology, genetics, immunology, biochemistry, radiology, etc. This disciplinary approach is reflected in this book. This new edition has been completely revised and brought up to date from the 20th to the 21st century. Basic neuroscientists were invited to contribute chapters explaining and describing basic scientific principles underlying the neuropathological disciplines. Also, additional information is provided concerning medic-legal issues, neuropharmacology, and a list of support groups for the elderly neurologically or mentally impaired in Brazil, Canada, Germany, the United Kingdom, and the USA. |
Contents
1 | |
Molecular Biology of the Aging Nervous System | 16 |
In Vivo Physiologic Imaging of Cerebral Ischemia | 42 |
Cerebrovascular Disease in the Elderly | 58 |
Vascular Dementia | 101 |
Basic Mechanisms of Neurodegeneration in Dementia | 123 |
Dementia | 156 |
Alzheimers Disease | 207 |
Brain Tumors in the Elderly | 408 |
Neurometabolic Disorders and the Aging Human Nervous System | 429 |
Immunologic Diseases of the Aging Nervous System | 446 |
Brain Trauma in the Elderly | 458 |
Infectious Diseases | 474 |
Peripheral Neuropathies | 499 |
The Aging Autonomic nervous System | 527 |
Pathology of Skeletal Muscle in Aging | 546 |
Parkinsons Disease | 264 |
The Scientific Basis of Parkinsonian Syndromes | 309 |
Degenerative Diseases of the Cerebellum | 322 |
Immunocytochemistry and Molecular Genetics of Amyotrophic Lateral Sclerosis | 360 |
Huntington Disease with Emphasis on Late Onset and Aging | 369 |
Effects of Malnutrition and Alcoholism on the Aging Nervous System | 392 |
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Common terms and phrases
abnormal Acta Neuropathol Berl adult age-related Alzheimer disease Alzheimer's disease Ann Neurol antibodies apoptosis Arch Neurol artery Aẞ associated astrocytes ataxia atrophy axonal basal ganglia Brain Res cause cells cellular cerebellar cerebral cortex changes chromosome chronic Clin clinical correlation cortical Creutzfeldt-Jakob disease decrease degeneration dementia demyelinating diagnosis disorders elderly factors fibers frontal function gene genetic glial gliosis glucose hematoma hemorrhage hippocampal histological human huntingtin Huntington's Huntington's disease increased infarcts injury involvement ischemic lesions Lewy bodies lobe meningitis metabolism mitochondrial molecular motor muscle mutations myelin nervous system neuritic Neurobiol neurodegenerative neurofibrillary tangles Neurol Sci Neurology neuronal loss neurons Neuropathol Exp Neurol Neurosci normal nucleus occur onset oxidative stress Parkinson's disease Pathol pathological patients peripheral Pick bodies Pick's disease plaques protein Purkinje cells receptors senile spinal spinocerebellar stain stroke subcortical substantia nigra synaptic syndrome tion tissue tumors ubiquitin vascular white matter