Battling Resistance to Antibiotics and Pesticides: An Economic Approach

Front Cover
Ramanan Laxminarayan
Resources for the Future, 2003 - 377 pages
The increasing resistance of bacteria to antibiotics, and pests to pesticides, threatens to undo some of the most remarkable advances made in public health and agriculture during the past century. Though the potential consequences of increased antibiotic and pesticide resistance are far reaching, regulatory efforts to address the problem are at a very early stage. Battling Resistance to Antibiotics and Pesticides moves such discussions forward by presenting cutting edge research and the first comprehensive application of economic tools to analyze how antibiotics and pesticides should be used to maximize their value to society. Laxminarayan and his contributors explore lessons from past experiences with resistance, especially in agriculture. They consider what incentives would be ideal for the individuals who prescribe or apply antibiotics and pesticides, and what would be ideal for the firms engaged in developing and producing these products. The chapters in this groundbreaking book reflect the fact that efforts to combat resistance will require contributions from a broad range of scholars and professionals, representing a broad range of expertise. The analysis demonstrates that, for all these participants, an understanding of economic issues is an essential complement to knowledge of medical or biological factors. The book provides economists with an overview of relevant scientific issues, as well as a variety of analytical approaches to studying the economics of resistance. It offers policymakers detailed analyses of the multiple dimensions of resistance and discusses the future strategies to combat and manage resistance. For professionals in medicine, public health, and agriculture, the book translates the economic approaches into usable guidance for daily practice and decisionmaking.

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Contents

Ecological versus Interventionist
17
Using Antibiotics When Resistance Is Renewable
42
Value of Treatment Heterogeneity for Infectious Diseases
63
To Take or Not To Take the Antibiotic?
76
Pest Mobility Market Share and the Efficacy of Refuge Requirements
94
Need for Direct Collaboration between Economists
113
The Impact of Resistance on Antibiotic Demand in Patients
119
Measuring the Cost of Resistance
134
The Role of Ecosystem Complexity in Genetically
158
Can We Justify Resistance Management Strategies
180
Economics of Transgenic Crops and Pest Resistance
238
Does the Monopolist Care about Resistance?
288
Industrial Organization and Institutional Considerations
330
Strategic Issues in Agricultural Pest Resistance Management
357
About the Editor 377
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About the author (2003)

Ramanan is a senior fellow at Resources for the Future in Washington, DC. His research includes the integration of epidemiological models of infectious disease transmission and the economic analysis of public health problems. He has worked with the World Health Organization on evaluating malaria treatment policy in Africa, and recently served on a National Academy of Science/Institute of Medicine Committee on the Economics of Anti-malarial Drugs. He teaches international health policy in the Johns Hopkins Bloomberg School of Public Health, and development economics at the Johns Hopkins University's Paul H. Nitze School of Advanced International Studies.

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