TYPES OF ASSISTANCE: PROJECT GRANTS USES AND USE RESTRICTIONS: Grants and cooperative agreements may be made to eligible institutions for the support of cancer research projects. The grants may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and indirect costs. SBIR Phase I grants (of approximately 6-months duration) are to establish the technical merit and feasibility of a proposed research effort that may lead to a commercial product or process. Phase II grants are for the continuation of the research initiated in Phase I, and that are likely to result in commercial products or processes. Only Phase I awardees are eligible to receive Phase II support. STTR Phase I grants (normally of 1-year duration) are to determine the scientific, technical, and commercial merit and feasibility of the proposed cooperative effort that has potential for commercial application. Phase II funding is based on results of research initiated in Phase I and scientific and technical merit and commercial potential of Phase II application. The SBIR Fast-Track Initiative provides additional assistance to applicants by expediting the decision and award of SBIR Phase II funding for scientifically meritorious applications for projects that have a high potential for commercialization. Fast-Track is a parallel option whereby Phase I and Phase II projects are reviewed concurrently with the aim of reducing or eliminating the funding gap between Phase I and Phase II. Applicant Eligibility: The awardee will be a university, college, hospital, public agency, nonprofit research institution, or for-profit organization that submits an application and receives a grant or cooperative agreement for support of research by a named principal investigator. SBIR grants can be awarded only to domestic small businesses (entities that are independently owned, and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees) which "partner" with a research institution in cooperative research and development. At least 40 percent of the project is to be performed by the small business concern and at least 30 percent by the research institution. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. Beneficiary Eligibility: Any nonprofit or for-profit organization, company, or institution engaged in biomedical research. Credentials/Documentation: For-profit organizations' cost are determined in accordance with 48 CFR, Subpart 31.2 of the Federal Acquisition Regulations. Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For other grantees, costs will be determined in accordance with HHS Regulations 45 CFR, Part 74, Subpart Q. For SBIR and STTR grants, applicant organization (small business concern) must present in a research plan an idea that has potential for commercialization and furnish evidence that scientific competence, experimental methods, facilities, equipment, and funds requested are appropriate to carry out the plan. Grant form SF424 is used to apply for SBIR Phase I and Phase II, respectively. Grant form SF424 is also used to apply for STTR Phase I and Phase II, respectively. See the website for more information on electronic submission of grants. http://grants.nih.gov/grants/funding/424/index.htm. OMB Circular No. A-87 applies to this program. Preapplication Coordination: Preapplication coordination is not applicable. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372. Application Procedures: This program is excluded from coverage under OMB Circular No. A-102. OMB Circular No. A-110 applies to this program. Application form PHS-398 is the standard form which may be obtained electronically from: http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. The standard application forms required by 45 CFR, Part 92 for State and local governments, must be used for this program. SBIR and STTR Grant Solicitations and SBIR Contract Solicitation may be obtained electronically through the NIH's "Small Business Funding Opportunities" home page at http://www.nih.gov/grants/funding/sbir.htm on the Web. Solicitations include submission procedures, review considerations, and grant application or contract proposal forms. SBIR and STTR grant applications should be submitted to the Center for Scientific Review, 6701 Rockledge Drive, Room 1040-MSC 7710, Bethesda, MD 20892-7710. Award Procedure: Approved grants and cooperative agreements are funded based on scientific merit, program relevance, and program balance and are made annually. Initial award provides funds for the first budget period (usually 12 months) and Notice of Grant Award (Form PHS 1533) indicates support recommended for remainder of project period, allocation of Federal funds by budget categories, and special conditions, if any. All accepted SBIR/STTR applications are evaluated for scientific and technical merit by an appropriate scientific peer review panel and if they are recommended for further consideration, by a national advisory council or board. All applications receiving a priority score compete for available SBIR/STTR set-aside funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program balance among the areas of research. Deadlines: Contact the headquarters or regional office, as appropriate, for application deadlines. Range of Approval/Disapproval Time: Approximately 10 months. SBIR Applications: About 7-1/2 months. A principal investigator (P.I.) may question the substantive or procedural aspects of the review of his/her application with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page http://grants.nih.gov/grants/guide/notice-files/not97-232.html. Renewals: Applications submitted for renewal are reviewed and selected for funding on a competitive basis. Formula and Matching Requirements: This program has no statutory formula. Matching requirements are not applicable to this program. Grants and cooperative agreements: Average 3 to 4 years, maximum of 5 years. No program reports are required. No cash reports are required. Progress reports are required each year. An Annual financial status report is required 90 days after the end of the budget period. Special reports may be requested by the DHHS. Terminal reports are required 6 months after the end of the project. Expenditure reports are not applicable. Performance monitoring is not applicable. Audits: Not Applicable. Records: Expenditures and other financial records must be retained for 3 years from the day on which the grantee submits the last financial status report for the report period. Account Identification: 75-0849-0-1-550 - Treatment Research. Obligations: (Salaries) FY 08 $519,410,000; FY 09 est $539,863,000; FY 10 est $560,880,000 - (Grants) For RPG: FY 2008 $519,410,000; FY 2009 est $539,863,000; and FY 2010 est $560,880,000. For SBIR/STTR: FY 2008 $34,431,000; FY 2009 est $33,078,000; and FY 2010 est $37,092,000. Range and Average of Financial Assistance: Range: $964 to $4,943,916 Average: $433,564. PROGRAM ACCOMPLISHMENTS: Fiscal Year 2008: Competing FY 2008 RPG act. 320 awards which were 20.7 percent of applications received. Competing FY 2008 SBIR/STTR act.996 awards which were 35.2 percent of applications received. Fiscal year 2008 est. 1,260 total awards and FY 2009 est. 1,227 total awards. Fiscal Year 2009: Fiscal Year 2009: It is estimated that 1,260 total awards will be made in FY 2009. Fiscal Year 2010: Fiscal Year 2010: It is estimated that 1,227 total awards will be made in FY 2010.. REGULATIONS, GUIDELINES, AND LITERATURE: 42 CFR 52; 45 CFR 74; 45 CFR 92. Grants will be available under the authority of and administered in accordance with the PHS Grants Policy Statement and Federal regulations at 42 CFR 52 and 42 USC 241; Omnibus Solicitation of the Public Health Service for Small Business Innovation Research (SBIR) Grant and Cooperative Agreement Applications. Omnibus Solicitation of the National Institutes of Health for Small Business Technology Transfer (STTR) Grant Applications. Regional or Local Office: None. Not applicable. Headquarters Office: Catherine M. Battistone 6116 Executive Blvd., Rm. 8044, Rockville, Maryland 20852 Email: battistc@mail.nih.gov Phone: 3015941088 Website Address: http://www.nci.nih.gov. RELATED PROGRAMS: 93.393 Cancer Cause and Prevention Research; 93.394 Cancer Detection and Diagnosis Research; 93.396 Cancer Biology Research; 93.399 Cancer Control EXAMPLES OF FUNDED PROJECTS: Not Applicable. CRITERIA FOR SELECTING PROPOSALS: The major elements in evaluating applications include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation, originality, or societal importance of the proposed research; (5) the potential of the proposed research for commercial application; (6) the reasonableness of the budget requested for the work proposed; (7) the adequacy and suitability of the facilities and research environment; and (8) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. 93.396 CANCER BIOLOGY RESEARCH Cancer Biology Research FEDERAL AGENCY: National Institutes of Health, Department of Health and Human Services Public Health Service Act, Section 301, 410, and 411, Public Law 78-410, 42 OBJECTIVES: To provide fundamental information on the cause and nature of cancer in people, with the expectation that this will result in better methods of prevention, detection and diagnosis, and treatment of neoplastic diseases. Cancer Biology Research includes the following research programs: cancer cell biology, cancer etiology, structural biology and molecular applications, DNA and chromosomal aberrations, tumor biology and metastasis, and immunology andhematology. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to increase private sector commercialization of innovations derived from Federal participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer; increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. TYPES OF ASSISTANCE: PROJECT GRANTS USES AND USE RESTRICTIONS: Grants and cooperative agreements may be made to eligible institutions for the support of cancer research projects. The grants and cooperative agreements may be used for personnel, consultant costs, equipment, supplies, travel, patient costs, animals, alterations and renovations, miscellaneous items, and Facilities and Administrative Costs (formerly known as indirect costs). SBIR Phase I grants (of approximately 6-months' duration) are to establish the technical merit and feasibility of a proposed research effort that may lead to a commercial product or process. Phase II grants are for the continuation of the research initiated in Phase I and that are likely to result in commercial products or processes. Only Phase I awardees are eligible to receive Phase II support. STTR Phase I grants (normally of 1-year duration) are to determine the scientific, technical and commercial merit and feasibility of the proposed cooperative effort that has potential for commercial application. Phase II are for the continuation of the research initiated in Phase I that is likely to result in a commercial product. The SBIR/STTR Fast Track Initiative provides additional assistance to applicants by expediting the decision and award of SBIR Phase II funding for scientifically meritorious applications for projects that have a high potential for commercialization. Fast-Track is a parallel review option whereby Phase I and Phase II projects are reviewed concurrently with the aim of reducing or eliminating the funding gap between Phase I and Phase II. Applicant Eligibility: The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that submits an application and receives a grant for support of research by a named principal investigator. SBIR grants can be awarded only to domestic small businesses (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees) which "partner" with a research institution in cooperative research and development. At least 40 percent of the project must be performed by the small business concern and at least 30 percent by the research institution. In both Phase I and Phase II, the research must be performed in U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. Beneficiary Eligibility: Any nonprofit or for-profit organization, company, or institution engaged in biomedical research. Credentials/Documentation: Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For-profit organizations' costs are determined in accordance with Subpart 31.2 of the Federal Acquisition Regulations. For other grantees, costs will be determined in accordance with HHS Regulations 45 CFR Part 74, Subpart Q. For SBIR and STTR grants, applicant organization (small business concern) must present in a research plan an idea that has potential for commercialization and furnish evidence that scientific competence, experimental methods, facilities, equipment, and funds requested are appropriate to carry out the plan. Grant form SF424(R&R) is used to apply for SBIR Phase I and Phase II, STTR Phase I and Phase II grants, and Fast-Track. See the website for more information on the electronic submission of grants. http://grants.nih.gov/grants/funding/424/index.htm. OMB Circular No. A-87 applies to this program. Preapplication Coordination: Preapplication coordination is not applicable. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372. Application Procedures: This program is excluded from coverage under OMB Circular No. A-102. OMB Circular No. A-110 applies to this program. The NIH is in the process of a transition to fully electronic grant submission through Grants.gov (see http://era.nih.gov/ElectronicReceipt for details). Depending on the grant mechanism, either form PHS-398 (Rev. September 2004) or form SF424(R&R) (October 2005) is the standard form. Both can be obtained at http://grants1.nih.gov/grants/forms.htm. The standard application forms, as furnished by PHS and required by 45 CFR, Part 92 for State and local governments, must be used for this program. This program is subject to the provisions of 45 CFR, Part 92 for State and local governments and OMB Circular No. A-110 for nonprofit organizations, as appropriate. SBIR and STTR Grant Solicitations and SBIR Contract Solicitation may be obtained electronically through the NIH's "Small Business Funding Opportunities" home page at www.nih.gov/grants/funding/sbir.htm on the World Wide Web. The Solicitations include submission procedures, review considerations, and grant application or contract proposal forms. All competing SBIR and STTR grant applications must be submitted electronically via Grants.gov The following is a website address for NIH electronic submission of grant application information: http://era.nih.gov/Electronic Receipt/index.htm. Award Procedure: Grants and cooperative agreements are funded based on scientific merit, program relevance, and program balance and are made annually. The initial grant award provides funds for the first budget period (usually 12 months) and letter Notice of Award indicates support recommended for the remainder of the project period, allocation of Federal funds by budget categories and special conditions, if any. All accepted SBIR/STTR applications are evaluated for technical merit by an appropriate scientific review group and if they are recommended for further consideration, by a national advisory council. All applications receiving a priority score compete for available SBIR/STTR set-aside funds on the basis of scientific and technical merit and commercial potential of the proposed research, program relevance, and program balance among the areas of research. Deadlines: Aug 05, 2009 All Grants including renewals and supplements: April 5, August 5, December 5. Cooperative Agreements and contracts are usually submitted in response to a Request for Applications (RFA) or a Request for Proposals (RFP). The receipt date is stipulated in the RFA or RFP. Range of Approval/Disapproval Time: Regular Grants: Approximately 10 months. SBIR/STTR: Approximately 7-1/2 months. Appeals: A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/notice-files/not97-232.html. Renewals: Applications submitted for renewal are reviewed and selected for funding on a competitive basis. Formula and Matching Requirements: This program has no statutory formula. Matching requirements are not applicable to this program. Grants and Cooperative Agreements: Average 3 to 4 years, and a maximum of No program reports are required. No cash reports are required. Progress reports are required each year. Annual financial status report is required 90 days after the end of the budget period. Special reports may be requested by DHHS. Terminal reports are required 6 months after the end of a project. Expenditure reports are not applicable. Performance monitoring is not applicable. Audits: This program is excluded from coverage under OMB Circular No. A-133. "In accordance with the provisions of OMB Circular No. A-133 (Revised, June 27, 2003), Audits of States, Local Governments, and Nonprofit Organizations, nonfederal entities that expend financial assistance of $500,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $500,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133." In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal government officials. Records: Expenditures and other financial records must be retained for 3 years from the day on which the grantee submits the last financial status report for the report period. Account Identification: 75-0849-0-1-550 - Cancer Biology Research. Obligations: (Salaries) FY 08 $520,202,000; FY 09 est $560,404,000; FY 10 est $602,535,000 (Grants) RPG: FY 2008 $520,202,000; FY 2009 est $560,404,000; and FY 2010 est $602,535,000. SBIR/STTR: FY 2008 $9,847,000; FY 2009 est $10,628,000; and FY 2010 est $11,491,000. Range and Average of Financial Assistance: Range: $1,949 to $4,377,964 Average: $339, 115. PROGRAM ACCOMPLISHMENTS: Fiscal Year 2008: Competing FY 2008 RPG act. 326 awards, which were 19.1 percent of applications received. Competing FY 2008 SBIR/STTR act. 28 awards, which were 31.5 percent of applications received. . Fiscal Year 2009: Fiscal year 2009: It is estimated that 1,509 total awards will be made in FY 2009. Fiscal Year 2010: Discal year 2010: It is estimated that 1,489 total awards will be made in FY2010. REGULATIONS, GUIDELINES, AND LITERATURE: 42 CFR 52; 45 CFR 74; 45 CFR 92; Grants will be available under the authority of and administered in accordance with the PHS Grants Policy Statement and Federal regulations at 42 CFR 52 and 42 U.S.C. 241; Omnibus Solicitation of the Public Health Service for Small Business Innovation Research (SBIR) Grant and Cooperative Agreement Applications. Omnibus Solicitation of the National Institutes of Health for Small Business Technology Transfer (STTR) Grant Applications. Regional or Local Office: None. Headquarters Office: Catherine M. Battistone 6116 Executive Blvd., Rm. 8044, Rockville, Maryland 20852 Email: battistc@mail.nih.gov Phone: 3015941088 Fax: 3014020275 Website Address: http://www.nih.gov. RELATED PROGRAMS: Not Applicable. EXAMPLES OF FUNDED PROJECTS: Not Applicable. CRITERIA FOR SELECTING PROPOSALS: Not Applicable. 93.397 CANCER CENTERS SUPPORT GRANTS Cancer Centers Support Grants FEDERAL AGENCY: National Institutes of Health, Department of Health and Human Services Public Health Service Act, Section 305(a), 410, 411, and 414, Public Law 78-410, 42 U.S.C. 241, as amended; Public Law 100-607, 42 U.S.C. 285, 285a and 285a-3; Public Law 99-500. OBJECTIVES: To provide an organizational focus and stimulus for the highest quality cancer research that effectively promotes interdisciplinary cancer research aimed toward the ultimate goal of reducing cancer incidence, mortality and morbidity. The Cancer Center Support Grant (CCSG) provides the resources and infrastructure to facilitate the coordination of interdisciplinary programs across a broad spectrum of research from basic laboratory research to clinical investigation to population science. The CCSG supports salaries for scientific leadership of the Center, shared resources for funded center investigators, certain administrative costs, planning and evaluation, and developmental funds for new recruitments and feasibility studies. TYPES OF ASSISTANCE: PROJECT GRANTS USES AND USE RESTRICTIONS: In general, CCSGs do not support research projects directly but are used to enhance the ongoing cancer research and to strengthen the existing research base according to the "Policies and Guidelines Relating to the Cancer Center Support Grant.". Applicant Eligibility: Any nonprofit institution within the United States with a peer-reviewed cancer research base of 4.0 million dollars in direct costs may apply for a Cancer Center Support Grant. Beneficiary Eligibility: University, college, public agency or research institution in the U.S. The application requests documentation concerning the qualifications of the principal investigators and associates, pertinent budget information and justification for the support of this proposed grant. Methods to be utilized are outlined in the application materials. Costs will be determined in accordance with HHS Regulations 45 CFR, Part 74, Subpart Q, and for State and local governments in accordance with OMB Circular No. A-87. OMB Circular No. A-87 applies to this program. Preapplication Coordination: Preapplication coordination is not applicable. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372. Application Procedures: This program is excluded from coverage under OMB Circular No. A-102. OMB Circular No. A-110 applies to this program. Method of Application: Form PHS-398 (Rev. May 2001) can be obtained from the, Division of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892-7910. Telephone (301)435-0714; e-mail ASKNIH@odrockml.od.nih.gov. In addition, supplemental instructions for applications are contained in the Cancer Center Support Grant Guidelines which can be obtained by writing to the Cancer Centers Branch, 6116 Executive Boulevard, Suite 700, MSC 8345, Bethesda, MD 20892-8345 or by calling (301)496-8531. Generally, the potential applicant should send a letter of intent to the National Cancer Institute, submitting a CCSG application to the same address for review (see Guidelines for CCSGs). Completed applications should be submitted to the Center for Scientific Review, National Institutes of Health, 6701 Rockledge Drive, Bethesda, MD 20892. This program is subject to the provisions of 45 CFR, Part 92 for State and local governments and OMB Circular No. A-110 for nonprofit organizations. Award Procedure: Grants are funded based on scientific merit, program relevance, and program balance and are made annually. Initial award provides funds for the first budget period (usually 12 months) and Notice of Grant Award (Form PHS 1533) indicates support recommended for the remainder of the project period, allocation of Federal funds by budget categories and special conditions, if any. Deadlines: Oct 01, 2009 Cancer Center Support Grant Applications (P30 mechanism): Renewals, New and Supplemental: February 1, June 1, and October 1. Cancer Center Planning Grant Applications (P20 mechanism): No new applications are accepted. Range of Approval/Disapproval Time: Core Grants: Approximately 10 months. A principal investigator may question the substantive or procedural aspects of the review of his/her application by communicating with the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/1997/97.11.21/n2.html. Renewals: Same procedure as new applications. This program has no statutory formula. Matching requirements are not applicable to this program. Up to 5 years of support may be requested. Grants may be awarded up to 5 Reports: No program reports are required. No cash reports are required. Progress reports are required each year. An annual financial status report is requested 90 days after the end of the budget period. Special reports may be requested by DHHS. Terminal reports are required 90 days after the end of a project. No expenditure reports are required. No performance monitoring is required. Audits: No audits are required for this program. Records: Expenditures and other financial records must be retained for 3 years from the day on which the grantee submits the last financial status report for the report period. Account Identification: 75-0849-0-1-550. Obligations: (Salaries) FY 08 $477,034,000; FY 09 est $489,204,000; FY 10 est $510,703,000 (Grants) (Total Research Centers) FY 2008 $477,034,000; FY 2009 est $489,204,000; and FY 2010 est $510,703,000. Range and Average of Financial Assistance: Range: $1,000 to $13,879,527 Average: $2,510,705. PROGRAM ACCOMPLISHMENTS: Fiscal Year 2008: Fiscal year 2008 Centers funded 190 total research Centers which included 63 Cores, 62 SPORES and 5 Specialized Centers. Centers. Cancer Centers are supported through the P30 grant mechanism as Cancer Center Support Grants (CCSGs), which fall into two categories as follows: cancer centers and comprehensive cancer centers. Policies and guidelines governing the main instrument of support, the Cancer Center Support Grant, have recently been revised. The P20 Cancer Center Planning Grants have been discontinued. However, considerable progress is being made in working with smaller, less research intensive institutions in areas of the country that have no NCI-designated cancer centers. The NCI will work with these institutions very closely in the future. Fiscal Year 2009: Fiscal year 2009 will fund an estimated 175 total Centers which will include 61 Cores, 59 SPORES and 5 Specialized Centers. Fiscal Year 2010: Fiscal year 2010 will fund an estimated 181 total Centers which will include 61 Cores, 59 SPORES and 5 Specialized Centers. REGULATIONS, GUIDELINES, AND LITERATURE: 42 CFR 52; 45 CFR 74; 45 CFR 92; PHS Grants Policy Statement, DHHS Publication No. (OASH) 90- 50,000, (Rev.) October 1, 1990. Regional or Local Office: None. None. Headquarters Office: Catherine M. Battistone 6116 Executive Blvd., Rm. 8044, Rockville, Maryland 20852 Email: battistc@mail.nih.gov Phone: 3015941088 Website Address: http://cancercenters.cancer.gov/. RELATED PROGRAMS: Not Applicable. EXAMPLES OF FUNDED PROJECTS: Fiscal Year 2008: CCSG awards to Memorial Sloan-Kettering Institute (comprehensive cancer center); to University of Alabama (comprehensive cancer center), to the St. Jude Children's Research Hospital (cancer center), to the University of Utah (cancer center), to the Salk Institute (cancer center), and to the Wistar Institute (cancer center). Fiscal Year 2009: No Current Data Available Fiscal Year 2010: No Current Data Available CRITERIA FOR SELECTING PROPOSALS: The major elements in evaluating applications include the following: (1) An adequate base of established programs of high quality in laboratory and clinical cancer research; (2) research activity in a variety of disciplines, and evidence of high degree of interdisciplinary coordination, interaction and cooperation among center members; (3) appropriate and adequate organization and facilities for the conduct and evaluation of center activities; (4) a qualified director with adequate authority; and (5) an adequate commitment of the parent institution or institutions to the cancer center. The center should be recognized as a major element within the organizational structure. 93.398 CANCER RESEARCH MANPOWER Cancer Research Manpower FEDERAL AGENCY: National Institutes of Health, Department of Health and Human Services AUTHORIZATION: Public Health Service Act, Sections 413 and 487, as amended, Public Law 100-607, 42 U.S.C. 285a, 42 U.S.C. 288. OBJECTIVES: To make available support to nonprofit and for-profit institutions interested in providing biomedical training opportunities for individuals interested in careers in basic, clinical, and prevention research important to the National Cancer Program. TYPES OF ASSISTANCE: PROJECT GRANTS USES AND USE RESTRICTIONS: The Research Manpower program provides support for research training in all scientific fields related to cancer. The Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Fellows, are made directly to individuals for research training in biomedical sciences areas. In addition, the National Institutes of Health (NIH) will award the Ruth L. Kirschstein NRSA Institutional Research Training grants to institutions, to enable them to make NRSA awards to individuals selected by them. Each individual who receives a postdoctoral NRSA is obligated, upon termination of the award, to comply with certain service and payback provisions. Cancer Education Grants are designed to promote education programs carried out by organizations engaged in health-related education, research, or training, located in the United States, its possessions, or territories. Various Career awards are designed to sponsor the development of independent scientists. Individual short-term support for students is available under the Cancer Education Program. Applicant Eligibility: University, college, hospital, public agency, or nonprofit research institution for institutional grants and individuals for fellowships. The applicant institution must be able to provide the staff and facilities and be responsible for the selection of trainees and overall direction of the training. Selected awardees must be citizens of the United States or be admitted to the United States for permanent residency. Career and Cancer Education awards may be given to for-profit institutions. Beneficiary Eligibility: University, college, hospital, public agency, nonprofit research institution or for-profit institution. Credentials/Documentation: (1) Individual Ruth L. Kirschstein NRSAS: The applicant's academic record, research experience, citizenship, institutional sponsorship, and the proposed area and plan of training must be included in the application. (2) Institutional Ruth L. Kirschstein NRSAS: Applicants must show the objectives, methodology, and resources for the training program, the qualifications and experience of directing staff, the criteria to be used in selecting individuals for award and a detailed budget and justification for the amount of grant funds requested. (3) Institutional Cancer Education Grants: Applicants must describe the organization and administration of the proposed program, list and define institutional objectives, methodology, resources and techniques of evaluation, as well as a justification of proposed expenditures. (4) For Career awards, the applicant must provide documentation on the candidate, sponsor, career development plan, research proposed, and institutional commitment. This program is excluded from coverage under OMB Circular No. A-87. Preapplication Coordination: Preapplication coordination is not applicable. Environmental impact information is not required for this program. This program is excluded from coverage under E.O. 12372. Application Procedures: This program is excluded from coverage under OMB Circular No. A-102. OMB Circular No. A-110 applies to this program. Applications for the Individual Ruth L. Kirschstein NRSA must be prepared using the PHS 416-1 application form and instructions for Individual National Research Service Award Fellowships (rev. 10/05). The PHS 416-1 is available at |