simply soaking in a water of ammonia, dilu'ed with twice its bulk of fresh water, and that this does not injure the rubber in any way, and restores th⚫ elasticity. Usually, soaking from ten minutes to half an hour is quite sufficient. After drying, the whiteness may be restored by dusting well with chalk or kaolin.

HABITUAL MISCARRIAGE.

Dr. Rasquinet, Jupile, near Liege, Belgium, says: "I tried Aletris Cordial in the case of a woman who had had several miscarriag s at the end of five months, and who is now again pregnant, having reached the seventh month. Thanks to Aletris Cordial."

FOR the treatment of Hernia, write to the Hernosine Chemical Co., Rochester, Mich.

THE Elixir Six Iodides is prepared by the WalkerGreen Pharmacal Co., Kansas City, Mo.

THIS is the season for whooping cough. Send $1 for a box of Pertussis Tablets, to Dr. W. H. Walling, 1606 Green street, Philadelphia.

ATROPINE, the active principle, is more efficacious than the tincture of belladonna, but the trouble is to dispense it accurately in the exceedingly small doses required. Send 10 cts. to the Phila. Granule Co., No. 10 South 18th St.. Phila lelphia, Pa., for 100 (or 65 cts. for 1000) of their elegant, accurate and economical granules of atropine. After using these you will never again go back to the crude preparations.

DEAL with I. Phillips, 69 Whitehall street, Atlanta, Ga., for cut rates in surgical instruments.

THE belief is becoming more general among physicians that tuberculosis is a non inheritable disease.Kan. Med. Jour.

FLUID Extract of Kola is a valuable tonic stimulant, indicated in nervous depression. Unfortunately, however, it is acrid and bitter in taste, and taken in this form is decidedly unpalatable. Messrs. Frederick Stearns & Co., of Detroit, Mich., have devised a compound which they call "Stearns' Kola Cordial," which is one-fourth the strength of the Fluid Extract, each fluidounce representing 120 gains of Kola, but is free from the acrid bitterness of the drug. It possesses the agreeable odor and characteristic taste of true Kola, and as a stimulant is prompt and active.

Physicians desiring to test this new product will be forwarded sufficient samples for clinical test on request.

FOR the antiseptic treatment of Hernia, address the Sthavara Co., 1224 Betz Building, Philadelphia.

See advertisement of Litmus Pencil. It will detect one part of acid or alkali to 100,000 parts of the fluid tested, while ordinary litmus paper will detect only in the proportion of one part to about 1400.

Will last perhaps a lifetime; always at hand and convenient.

impressed upon eaeh tablet to insure its genuineness. See adv. in this issue.

METRORRHAGIA.

T. Henson Smith, L. R. C. P. & L. R. C. S. & L. M., Reddish G een, near Stockport, England, says :"I have found the Aletris Cordial useful, chiefly in cases of irregular and difficult menstruations. In one case, a girl of twenty, who has been under my treatment a year with irregular and painful menstruation, I have been able to afford complete relief by giving the Aletris Cordial in teaspoonful doses, commencing about two days before the period, and during the time, of menstruation. I have also tried it in a case of dysmenorrhea, with megrimes. The result has been to remove the dysmenorrhea and relieve the headache. I have found it beneficial in many uterine cases.

JOHN S. LYNCH, M.D., Professor Principles and Practice of Medicine, and Clinical Professor of Heart, Throat and Lu gs in College of Physicians and Surgeons, writes:

"Dr. J. A. McArthur. My Dear Doctor:-I take this occasion to say that I used the Syrup of Hypophosphites, both in the in an out-patients' departments, and in all cases with very decided benefit. In every case emaciation was arrested, and in some there was a decided gain of flesh and strength, w th a corresponding improvement in the cough and other symp

toms.

"I now prescribe it habitually in my private prac tice, and always with benefit when the cases are properly selected."

CASCARA SAGRADA FOR THE BLIMINATION OF URIC ACID.

It seems to be the accepted opinion that the pathology of uric acid is more a matter of defective elimination than of excessive formation. Osler says:"Certain symptoms arise in connection with defective food or tissue metabolism, more particularly of the nitrogenous elements; and this faulty metabolism, if long continued, may lead to gout, with uratic deposits in the joints, acute inflammations, and arterial and renal disease."

Not getting the desired results, I was led to drop all the so called antilithics, and rely simply and solely upon a single remedy-Cascara Sagrada. Repeated trials have convinced me that the faulty metabolism is more quickly remedied with this drug alone than with any other or combinations.

Mrs. G., aged 55, was for years subject to uric acid storms, and without getting relief. I exhibited the aromatic fluid extract Cascara made by Parke, Davis & Co., in ten to fifteen drop doses, two or three times dily, as demanded, finally settling down to one single dose at the close of the day. The effect was not at once apparent, but within two weeks there was marked amelioration of the aggravated symptoms, and in four weeks the swollen joints had a most resumed a normal appearance, the sorene s having nearly disappeared. At this writing (two months having elapsed) there is no complaint whatever, but the remedy is continued. No change was made in the diet, as I desired to more fully test the remedy, and am fully satisfied that the good results were due solely to the Cascara. I have tried other brands of Cascara, but they have not been satisfactory, hence I have come to regard the fluid extract above alluded to as the only one upon which I can confidently rely. It never fails, hence my preference. DR. W. H. WALLING, in the Medical and Surgical Reporter, July 14th, 1894.

HORSFORD'S Acid Phosphate is a standard tonic in nervous dyspepsia or exhaustion. Sample to physieians who will pay express charges. Rumford Chemical Works, Providence, R. I.

WE have been acquainted with Horlick's Malted Milk since its introduction. We regard it as a valuable article. Samples to physicians. Horlick's Food Co., Racine, Wis.

MONTHLY PAYMENTS.

A physician in Missouri has this on his bill-heads and statements:

"We must have monthly payments, if we do your practice. If there is any mistake in this account, please call on us and we will cheerfully correct it."

WHEN you want to give iodine, give Hostelley's Syrup of Hydriodic Acid.

FEMALE EXTERNAL GENITAL ORGANS.

In the N. Y. Jour. of Gyn. and Obstet. for August, Dr. D. S. Lamb, of the Army Medical Museum, Washington, contributes a criticism on the current anatomical descriptions of the external genitals of woman. He finds that the external genitalia, including even the vagina itself, are not covered by mucous membrane, but by a modified skin. He also finds that the fourchette is formed by the labia minora.

THE Mellier Drug Company, of 2112 Lucas Place and 721 Locust street, St. Louis, appreciating the tendency towards a general decline in values, take the initiative with their Elliott Saddle- Bags, and, as will be seen by their advertisement, make the following very low prices:-Small, 24 vials, $6.00; large, 30 vials. $7.00, extra large, $8. Upon receipt of price the Elliott Saddle-Bags will be delivered, charges pre paid, to the nearest express office.

FOR Biliousness, Jaundice, etc, use Peacock's Chionia.

Dr. Robert G. Feek, of Hamilton, N. Y., writes:"William G-, who resides in the town of Dekalb, near Hamilton, St. Lawrence County, N. Y., was suffering from disease of the stomach about twenty-five years ago. He states that he spent all his earnings in doctoring till about twenty-one years ago, when he tried saleratus, which gave him relief. Since then he has used it constantly, and is now using the twentysecond hundred pounds. He carries it with him wherever be goes. He is sixty-one years of age, the father of eleven children, and does all the work of a farm of one hundred and ten acres, except an occasional extra help. He purchases his saleratus by the barrel. These statements are authentic, as inquiry will prove. The saleratus is taken in a dry state. At first it was taken in small quantities, but now in doses of one-half ounce, and to the quantity of over two pounds a week."-Med. Rec.

SEND for literature regarding Tri-Iodides and Three Chlorides, to Renz & Henry Pharmacal Co., Louisville, Ky.

SEND $1.00 for sample and formula of Amlar's Tobacco Antidote, to F. H. Amlar, Jackson, Mich.

The

The year has rolled around again, and with this issue thousands of subscriptions for this publication expire. The notice, "Your subscription expires with this number," will be found stamped on the front cover of the last issue for which you have paid. Has THE MEDICAL WORLD been worth its price to you during the past year? Do you think it will be worth its price to you during the coming year? If so, please don't procrastinate. If you wish to economize, send $3 for four years; if times are pinch. ing you unusually hard, send 25 cents or 50 cents (stamps will do) for three or six months, until it will be convenient for you to send the $1 or $3, and thus avoid missing any of the numbers. If you are too busy to send it yourself, hand the money to your postmaster, stating that you are an old subscriber, and he will send it for you. It will be easier for you to do it to-day than to-morrow.

The Typhoid State.

In the progress of a case of typhoid fever, when the intestinal ulcers are discharging their products into the bowel, to be from there absorbed and carried into the circulation, a condition of the patient develops known as the "typhoid state." It is characterized, in its typical form, by extreme debility; low, muttering delirium; dry, brown or blackish diminished tongue; dry, cracked lips; sordes on the teeth; weak, fluttering pulse; loss of control of urine and feces; impairment of speech and deglutition; muscular trembling and twitching; picking at the bed clothes or imaginary objects; breathing shallow and frequent; blunting of the special senses, as manifested by dimness of vision, slight deafness, and impaired taste and smell; capillary congestion and stagnation of the venous circulation, leading to low grades of superficial inflammation and the formation of bed-sores; Joss of muscular control, allowing the patient to constantly sink towards the foot of the bed. In many cases this extreme development does not occur, a much milder form being observed.

Until recent developments in pathology were made, the cause of this condition was not known, although the clinical fact was well recognized. It was formerly taught that the cause was the long continuance of high temperature. Now it is conceded that the cause of the phenomena of the typhoid condition (as also of the prolonged high fever itself) is found in a profound poisoning of the central nervous system by the ptomaines or "anti-toxines" developed by the disease germs at the seat of their activity, and carried throughout the system by the blood. These ptomaines are the products of the life-processes of the specific disease germs, and are destined in time, if they do not kill the patient, to destroy the germs themselves. The germs of each one of the infectious diseases manufacture a ptomaine peculiar to themselves,